SMART Medical Review: Acute Pancreatitis Assessment and Management in the First 24 Hours

Acute Pancreatitis First 24 hours

Authors

  • Peter Lee The Ohio State University Wexner Medical Center Author
  • Shrinivas Bishu MD PhD Division of Gastroenterology and Hepatology, Department of Medicine, University of Michigan, Ann Arbor, MI Author
  • Cameron Breze Consultant, Ariel Precision Medicine, Pittsburgh, PA Author
  • Amitabh Chak MD Digestive Health Research Institute, Department of Medicine, Case Western Reserve Uni-versity, Cleveland, Ohio Author
  • Timothy B. Gardner MD Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH Author
  • Nalini M. Guda MD GI Associates, St. Luke's Medical Center, Milwaukee, WI Author
  • Vivek Kaul MD Division of Gastroenterology & Hepatology, University of Rochester Medical Center & Strong Memorial Hospital, Rochester, NY Author
  • Thiruvengadam Muniraj MD PhD FRCP Division of Digestive Diseases, Department of Medicine, Yale University School of Medicine, New Haven, CT Author
  • Georgios I. Papachristou MD PhD Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, The Ohio State University, Columbus Ohio Author
  • Beth Schrope MD PhD Department of Surgery, Columbia University College of Physicians and Surgeons, Washington Heights, NY Author
  • Daniel M. Spagnolo PhD Consultant, Ariel Precision Medicine, Pittsburgh, PA Author
  • Daniel S. Strand MD Department of Gastroenterology and Hepatology, Department of Medicine, University of Virginia, and UVA Health, System Charlottesville, VA Author
  • Paul Tarnasky MD Methodist Digestive Institute, Methodist Dallas Medical Center, Dallas, TX Author
  • Jason R. Taylor, MD Division of Gastroen-terology and Hepatology, Department of Medicine, Saint Louis University, Saint Louis, MO Author
  • C. Mel Wilcox MD Orlando Health Digestive Health Institute, Orlando, FL Author
  • David C Whitcomb MD PhD Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, Pittsburgh, PA Author

DOI:

https://doi.org/10.69734/7dcnna53

Keywords:

multiple organ failure, capillary leak syndrome, numerical analysis, abdominal pain, pancreatic digestive enzymes, pancreatic enzymes, Revised Atlanta Criteria, Marshall Score, Ranson's score, hypertriglyceridemia, hypercalcemia, genetics, SIRS, systemic inflammation, shock, hypovolemia, acute kidney injury, ARDS, clinical decision support, recommendations, consensus, BISAP, BMI, pleural effusion, hematocrit, gallstone, D010195, D009102, D019559, D009716, fatty acid

Abstract

Acute pancreatitis (AP) is an inflammatory reaction of the pancreas caused by inappropriate trypsin activation and an injury / innate inflammatory response. The many etiologies and potentially life-threatening consequences of AP require that clinicians initiate prompt and individualized treatment upon diagnosis. Application of new advances in the management of AP are required at the point of care. To facilitate care, a group of clinical experts have developed a set of recommendations for the evaluation and management of AP during the first 24 hours based on current evidence and evolving concepts.  Ten areas of care are addressed where expert recommendations may be useful: (1) physical examination, (2) laboratory tests, (3) diagnosis, (4) early treatment, (5) severity determination, (6) etiology-based management, (7) typical orders sets, (8) determining of appropriate level of care, (9) quality of care, and (10) quality improvement recommendations. Conclusion: These recommendations should become available as clinical decision support tools that are accessible at the point of care, in real time.

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Published

2024-09-30

How to Cite

Lee, P., Bishu, S., Breze, C., Chak, A., Gardner, T., Guda, N., Kaul, V., Muniraj, T., Papachristou, G., Schrope, B., Spagnolo, D., Strand, D., Tarnasky, P., Taylor, J. R., Wilcox, C. M., & Whitcomb, D. (2024). SMART Medical Review: Acute Pancreatitis Assessment and Management in the First 24 Hours: Acute Pancreatitis First 24 hours. SMART-MD Journal of Precision Medicine, 1(2), e19 - e48. https://doi.org/10.69734/7dcnna53